Which factor is relevant to an individual's predisposition to substance use disorders?

The relevance of genetic history to an individual's predisposition to substance use disorders is well-documented in research. Genetics can significantly impact a person's vulnerability to addiction by influencing how they respond to drugs, their likelihood of engaging in addictive behaviors, and their overall susceptibility to developing substance use disorders. This inherited risk can manifest through various biological mechanisms, such as neurotransmitter regulation and mood disorders, which are common among those with a family history of addiction.

While environmental influences, personality traits, and social skills can also play roles in a person's risk factors for addiction, they do not specifically address the inherent biological predisposition that genetic history encapsulates. Understanding this genetic component helps professionals assess the risk and tailor interventions more effectively.