What role does tolerance play in substance abuse?

Tolerance is a critical concept in understanding substance abuse because it refers to the body's adaptation to a drug after prolonged use. As individuals consume a substance over time, their bodies may become less sensitive to its effects. This means that the same amount of the substance will produce a diminished response compared to when the person first started using it. Therefore, individuals often find that they need to consume larger quantities of the substance to achieve the same effects, which can lead to increased usage and further dependence.

This process plays a significant role in the progression of substance abuse, as individuals may escalate their intake in an attempt to regain the initial effects they experienced. Tolerance can contribute to a cycle of increasing use, dependence, and potential withdrawal symptoms when the substance is not available. Understanding tolerance is crucial for recognizing the physiological adaptations that occur with chronic substance use and their implications for treatment and recovery.